User profiles for Kristen K Comfort

Kristen Krupa (formerly Kristen Comfort)

University of Dayton
Verified email at udayton.edu
Cited by 969

At the Crossroads of Nanotoxicology in vitro: Past Achievements and Current Challenges

…, DB Warheit, SP Ng, KK Comfort…�- Toxicological�…, 2015 - academic.oup.com
The exponential growth in the employment of nanomaterials (NMs) has given rise to the field
of nanotoxicology; which evaluates the safety of engineered NMs. Initial nanotoxicological …

Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells

KK Comfort, EI Maurer, LK Braydich-Stolle…�- ACS�…, 2011 - ACS Publications
Metallic nanomaterials, including silver, gold, and iron oxide, are being utilized in an
increasing number of fields and specialties. The use of nanosilver as an antimicrobial agent is …

Less Is More: Long-Term in Vitro Exposure to Low Levels of Silver Nanoparticles Provides New Insights for Nanomaterial Evaluation

KK Comfort, LK Braydich-Stolle, EI Maurer…�- ACS�…, 2014 - ACS Publications
In view of the vast number of new nanomaterials (NMs) that require testing and the constraints
associated with animal models, the majority of studies to elucidate nanotoxicological …

Modification of the protein corona–nanoparticle complex by physiological factors

…, MC DeBrosse, SM Hussain, KK Comfort�- Materials Science and�…, 2016 - Elsevier
Nanoparticle (NP) effects in a biological system are driven through the formation and
structure of the protein corona–NP complex, which is dynamic by nature and dependent upon …

Tannic acid coated gold nanorods demonstrate a distinctive form of endosomal uptake and unique distribution within cells

EA Untener, KK Comfort, EI Maurer…�- …�Applied Materials &�…, 2013 - ACS Publications
One of the primary challenges associated with nanoparticle-dependent biological applications
is that endosomal entrapment in a physiological environment severely limits the desired …

Toxicological implications of platinum nanoparticle exposure: Stimulation of intracellular stress, inflammatory response, and akt signaling in vitro

…, LK Braydich-Stolle, KK Comfort�- Journal of�…, 2018 - Wiley Online Library
Due to their distinctive physicochemical properties, platinum nanoparticles (PtNPs) have
emerged as a material of interest for a number of biomedical therapeutics. However, in some …

[HTML][HTML] Novel platform development using an assembly of carbon nanotube, nanogold and immobilized RNA capture element towards rapid, selective sensing of�…

EI Maurer, KK Comfort, SM Hussain, JJ Schlager…�- Sensors, 2012 - mdpi.com
This study examines the creation of a nano-featured biosensor platform designed for the rapid
and selective detection of the bacterium Escherichia coli. The foundation of this sensor is …

Slow release of ions from internalized silver nanoparticles modifies the epidermal growth factor signaling response

KK Comfort, EI Maurer, SM Hussain�- Colloids and surfaces B�…, 2014 - Elsevier
Due to their distinctive physiochemical properties, including a robust antibacterial activity and
plasmonic capability, hundreds of consumer and medical products contain colloidal silver …

[HTML][HTML] Preliminary protein corona formation stabilizes gold nanoparticles and improves deposition efficiency

AO Luby, EK Breitner, KK Comfort�- Applied Nanoscience, 2016 - Springer
Due to their advantageous characteristics, gold nanoparticles (AuNPs) are being
increasingly utilized in a vast array of biomedical applications. However, the efficacy of these …

Immunogenicity and antimicrobial effectiveness of Pseudomonas aeruginosa specific bacteriophage in a human lung in vitro model

JR Shiley, KK Comfort, JB Robinson�- Applied microbiology and�…, 2017 - Springer
The rise of antibiotic resistant bacteria is posing a serious threat to human health. For
example, resistant strains of Pseudomonas aeruginosa have resulted in untreatable and …