The patch clamp technique, developed in late 1970s, started a new period of experimental
cardiac electrophysiology enabling measurement of ionic currents on isolated …

Acute excessive ethyl alcohol (ethanol) consumption alters cardiac electrophysiology and
can evoke cardiac arrhythmias, eg, in ‘holiday heart syndrome’. Ethanol acutely modulates …

Alcohol consumption may result in electrocardiographic changes and arrhythmias. Important
role of modifications of the inward rectifier potassium current IK1 in arrhythmogenesis is …

The sarcolemmal Ca 2+ efflux pathways, Na + -Ca 2+ -exchanger (NCX) and Ca 2+ -ATPase
(PMCA), play a crucial role in the regulation of intracellular Ca 2+ load and Ca 2+ transient …

The antiarrhythmic action of the newly developed compound 44Bu (an original compound
that was synthesized at our Faculty of Pharmacy) was tested on a model of aconitine-induced …

The combination of aminophylline and salbutamol is frequently used in clinical practice in the
treatment of obstructive lung diseases. While the side effects (including arrhythmias) of the …

Aim: Even though alcohol intoxication is often linked to arrhythmias, data describing ethanol
effect on cardiac ionic channels are rare. In addition, ethanol is used as a solvent of …

Two mechanisms are generally proposed to explain right precordial ST-segment elevation
in Brugada syndrome: 1) right ventricular (RV) subepicardial action potential shortening and/…

Traditionally, aborted cardiac arrest (ACA) due to documented ventricular fibrillation (VF) in
the absence of structural heart disease has been termed idiopathic VF. By careful evaluation, …

In many addictive drugs including alcohol and nicotine, proarrhythmic effects were reported.
This review provides an overview of the current knowledge in this field (with a focus on the …