Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport—an update
Q Mao, JD Unadkat�- The AAPS journal, 2015 - Springer
The human breast cancer resistance protein (BCRP, gene symbol ABCG2) is an ATP-binding
cassette (ABC) efflux transporter. It was so named because it was initially cloned from a …
cassette (ABC) efflux transporter. It was so named because it was initially cloned from a …
Structure and function of the human breast cancer resistance protein (BCRP/ABCG2)
…, Z Bikadi, MF Rosenberg, Q Mao�- Current drug metabolism, 2010 - ingentaconnect.com
The human breast cancer resistance protein (BCRP/ABCG2) is the second member of the G
subfamily of the large ATPbinding cassette (ABC) transporter superfamily. BCRP was …
subfamily of the large ATPbinding cassette (ABC) transporter superfamily. BCRP was …
[HTML][HTML] BCRP/ABCG2 in the Placenta: Expression, Function and Regulation
Q Mao�- Pharmaceutical research, 2008 - Springer
Abstract Knowledge concerning transport of maternally administered drugs across the placental
barrier is essential for determining potential toxicity of drugs to the fetus and the value of …
barrier is essential for determining potential toxicity of drugs to the fetus and the value of …
Role of the breast cancer resistance protein (ABCG2) in drug transport
Q Mao�- The AAPS journal, 2005 - Springer
The 72-kDa breast cancer resistance protein (BCRP) is the second member of the subfamily
G of the human ATP binding cassette (ABC) transporter superfamily and thus also …
G of the human ATP binding cassette (ABC) transporter superfamily and thus also …
HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2)
Breast cancer resistance protein (BCRP) is a recently discovered ATP-binding cassette drug
transporter. Hence, the full spectrum of therapeutic agents that interact with BCRP remains …
transporter. Hence, the full spectrum of therapeutic agents that interact with BCRP remains …
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
The 190-kDa phosphoglycoprotein multidrug resistance protein 1 (MRP1) (ABCC1) confers
resistance to a broad spectrum of anticancer drugs and also actively transports certain …
resistance to a broad spectrum of anticancer drugs and also actively transports certain …
Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells
…, Y Zhang, JD Unadkat, Q Mao�- American Journal�…, 2006 - journals.physiology.org
The breast cancer resistance protein (BCRP) is abundant in the placenta and protects the
fetus by limiting placental drug penetration. We hypothesize that pregnancy-specific hormones …
fetus by limiting placental drug penetration. We hypothesize that pregnancy-specific hormones …
[HTML][HTML] Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity
…, VS Sidorenko, A Chapron, CK Yeung, C Gao, Q Mao…�- JCI insight, 2017 - ncbi.nlm.nih.gov
Environmental exposures pose a significant threat to human health. However, it is often
difficult to study toxicological mechanisms in human subjects due to ethical concerns. Plant-…
difficult to study toxicological mechanisms in human subjects due to ethical concerns. Plant-…
[HTML][HTML] The structure of the multidrug resistance protein 1 (MRP1/ABCC1): crystallization and single-particle analysis
MF Rosenberg, Q Mao, A Holzenburg, RC Ford…�- Journal of Biological�…, 2001 - ASBMB
Multidrug resistance protein 1 (MRP1/ABCC1) is an ATP-binding cassette (ABC) polytopic
membrane transporter of considerable clinical importance that confers multidrug resistance …
membrane transporter of considerable clinical importance that confers multidrug resistance …
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma�…
…, PCK Leung, DD Ross, JD Unadkat, Q Mao�- Molecular�…, 2008 - ASPET
Breast cancer resistance protein (BCRP) plays a significant role in drug disposition and in
conferring multidrug resistance in cancer cells. Previous studies have shown that steroid …
conferring multidrug resistance in cancer cells. Previous studies have shown that steroid …