Saccharomyces boulardii is a nonpathogenic yeast used in the treatment of Clostridium difficile
diarrhea and colitis. We have reported that S. boulardii inhibitsC. difficile toxin A enteritis …

A small percentage of pathologically obese subjects with fatty livers develop histological signs
of necroinflammation and fibrosis, suggesting a variety of cofactors in the pathogenesis of …

Saccharomyces boulardii, a nonpathogenic yeast, is effective in treating some patients with
Clostridium difficile diarrhea and colitis. We have previously reported that S. boulardii inhibits …

Background: Saccharomyces boulardii is a nonpathogenic yeast used for the prevention and
treatment of Clostridium difficile-associated diarrhea and colitis. However, the mechanism …

Substance P, acting via the neurokinin 1 receptor (NK1R), plays an important role in mediating
a variety of inflammatory processes. However, its role in acute pancreatitis has not been …

We determined the effects of immobilization stress on rat colonic mucus release and mast cell
degranulation and examined whether corticotropin releasing factor (CRF) was involved in …

Background & Aims In the intestines, Toll-like receptor 2 (TLR2) mediates immune responses
to pathogens and regulates epithelial barrier function; polymorphisms in TLR2 have been …

Clostridium difficile toxin A causes acute neutrophil infiltration and intestinal mucosal injury.
In cultured cells, toxin A inactivates Rho proteins by monoglucosylation. In monocytes, toxin …

Toxin A from Clostridium difficile mediates acute inflammatory enterocolitis in experimental
animals, while cholera toxin causes noninflammatory secretory diarrhea. The purpose of this …

Activated hepatic stellate cells (HSCs) secrete extracellular matrix components during
hepatic fibrosis, but recent studies have shown that HSCs can also release a variety of …