Experiments on Wistar rats showed that cisplatin and carboplatin induced similar morphological
alterations in the ovaries. Both agents reduced the number of structural and functional …

The review gives summarized information on the preclinical data and clinical trials evaluating
the safety of the antiviral drug Kagocel. It notes that the manufacturer of the drug pay …

Morphological and functional characteristics of spermatogenesis in rats were studied during
the early and delayed periods after single injection of paclitaxel (antitumor agent) in the …

Here we review the results of experimental and clinical observations concerning the
gonadotoxic effect of antitumor chemotherapy. Previous experiments showed that antiblastic …

The effect of para-tyrosol (PT), a hydroxyalkylphenol exhibiting antioxidant properties, on
the level of DNA damage in testicular tissue cells and sperm of rats treated with doxorubicin …

The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology,
functions, and redox processes in the reproductive cells of male rats was studied on the …

The offspring of Wistar rats obtained from parents, one of which received platinum-containing
drug Platidiam (cisplatin) or anthracycline antibiotics Doxorubicin and Farmorubicin was …

The effect of p-tyrosol on the spontaneous level of DNA damage in the cells of the bone
marrow, liver, kidney, and rectum of mice (series I) and on the genotoxic effects of cytostatic …

We studied the effect of antioxidants dibornol (2,6-diisobornyl-4-methylphenol) and its derivative
(4-hydroxymethyl-2,6-diisobornylphenol), members of the alkylated phenols group, on …

A decrease in the total number of sperm cells and reduction of spermatogonium population
were observed upon cytostatic damage of spermatogenous tissue caused by single …