User profiles for Raul Bonne Hernandez

Ra�l B Hern�ndez

Prof. Dr. Universidade Federal de S�o Paulo
Verified email at unifesp.br
Cited by 499

Mechanisms of manganese-induced neurotoxicity in primary neuronal cultures: the role of manganese speciation and cell type

RB Hern�ndez, M Farina, BP Esp�sito…�- Toxicological�…, 2011 - academic.oup.com
Manganese (Mn) is an essential trace element required for the proper functioning of a variety
of physiological processes. However, chronic exposures to Mn can cause neurotoxicity in …

[HTML][HTML] Manganese-induced cellular disturbance in the baker's yeast, Saccharomyces cerevisiae with putative implications in neuronal dysfunction

RB Hern�ndez, H Moteshareie, D Burnside…�- Scientific Reports, 2019 - nature.com
Manganese (Mn) is an essential element, but in humans, chronic and/or acute exposure to
this metal can lead to neurotoxicity and neurodegenerative disorders including Parkinsonism …

[HTML][HTML] Chemical equilibrium in the complexation of first transition series divalent cations Cu2+, Mn2+ and Zn2+ with chitosan

RB Hern�ndez, OR Yola, ALR Merc�- Journal of the Brazilian�…, 2007 - SciELO Brasil
This study provided the data for calculating the stability constants formed in the aqueous HCl
equilibrium of chitosan and Cu2+, Mn2+ and Zn2+, and determined the species distribution …

[HTML][HTML] Manganese-Induced Neurotoxicity through Impairment of Cross-Talk Pathways in Human Neuroblastoma Cell Line SH-SY5Y Differentiated with Retinoic�…

RB Hern�ndez, NC de Souza-Pinto, J Kleinjans…�- Toxics, 2021 - mdpi.com
Manganese (Mn) is an important element; yet acute and/or chronic exposure to this metal has
been linked to neurotoxicity and neurodegenerative illnesses such as Parkinson’s disease …

[HTML][HTML] The psychoactive effects of Bryophyllum pinnatum (Lam.) Oken leaves in young zebrafish

…, A Melgoza, R Bonne Hern�ndez…�- PLoS�…, 2022 - journals.plos.org
Bryophyllum pinnatum (Lam.) Oken (BP) is a plant that is used worldwide to treat inflammation,
infections, anxiety, restlessness, and sleep disorders. While it is known that BP leaves …

Manganese-induced neurotoxicity in cerebellar granule neurons due to perturbation of cell network pathways with potential implications for neurodegenerative�…

RB Hern�ndez, M Carrascal, J Abian, B Michalke…�- Metallomics, 2020 - academic.oup.com
Manganese (Mn) is essential for living organisms, playing an important role in nervous
system function. Nevertheless, chronic and/or acute exposure to this metal, especially during …

[HTML][HTML] Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal�…

…, N Zare, S Takallou, T Naing, RB Hern�ndez…�- PLoS�…, 2018 - journals.plos.org
Heavy metal and metalloid contaminations are among the most concerning types of pollutant
in the environment. Consequently, it is important to investigate the molecular mechanisms …

Using the Layered Double Hydroxide-Lycopene Nanocomposite Formulation to Lessen Lycopene Toxicity in Danio rerio Embryos

NAG Rojas, RB Hern�ndez, RNM V�zquez…�- BioNanoScience, 2024 - Springer
Recently, we synthesized a layered double hydroxide-lycopene (LDH-lycopene)
nanocomposite to enhance the dispersibility of lycopene in aqueous media, which is one of the …

[PDF][PDF] Manganese-induced cellular disturbance in the baker's yeast, Saccharomyces cerevisiaewith putative implications in neuronal dysfunction

RB Hern�ndez, H Moteshareie, D Burnside, B McKay… - researchgate.net
Results To identify pathways that are influenced by Mn exposure, we screened for gene
deletion strains that demonstrate increased sensitivity to Mn2+ using the yeast non-essential …

Systems toxicology studies reveal important insights about chronic exposure of zebrafish to Kalanchoe pinnata (Lam.) Pers leaf-KPL: Implications for medicinal use

…, MU Nakamura, S Guo, RB Hern�ndez�- Journal of�…, 2025 - Elsevier
Ethnopharmacological relevance The prevalence of depression and anxiety is high during
pregnancy. Several traditional medicines use the plant Kalanchoe pinnata (Lam.) Pers. (KP) …