The in vivo Pig-a assay uses flow cytometry to measure phenotypic variants for antibody
binding to cell surface glycosylphosphatidylinositol (GPI)-anchored proteins. There is good …

Mouse lymphoma thymidine kinase gene mutation assay: Follow�•’up meeting of the
international workshop on Genotoxicity test Page 1 Meeting Report Mouse Lymphoma Thymidine …

Titanium dioxide is a ubiquitous white material found in a diverse range of products from
foods to sunscreens, as a pigment and thickener, amongst other uses. Titanium dioxide has …

Nanomaterials (NMs) present unique challenges in safety evaluation. An international
working group, the Genetic Toxicology Technical Committee of the International Life Sciences …

The International Workshop on Genotoxicity Testing (IWGT) meets every four years to seek
consensus on difficult or conflicting approaches to genotoxicity testing based upon …

A collaborative international trial was conducted to evaluate the reproducibility and
transferability of an in vivo mutation assay based on the enumeration of CD59‐negative rat …

In the course of discovering the first mutagen (X-rays) just over 60 years ago, Herman J.
Muller asked whether X-rays induced single-gene mutations and/or chromosomal (multiple-gene…

A database of 91 chemicals with published data from both transgenic rodent mutation (TGR)
and rodent comet assays has been compiled. The objective was to compare the sensitivity …

The Mouse Lymphoma Assay (MLA) Workgroup of the International Workshop on Genotoxicity
Tests (IWGT) met on June 28th and 29th, 2002, in Plymouth, England. This meeting of the …

AS52 cells are Chinese hamster ovary (CHO) cells that carry a single functional copy of the
bacterial gpt gene and allow the isolation of 6-thioguanine-resistant (6TG r )mutants arising …